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doi: 10.1016/j.jid.2021.10.012
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Assessing GPx activity in tissue homogenates (e.g., lung, pancreas) or cell lysates (e.g., airway epithelial cells) is vital for understanding its contribution to CF pathology in affected organs
To ensure surfactant renewal, the lung utilizes circulating fatty acids from the bloodstream, which undergo intracellular remodeling before being incorporated into surfactant synthesis and secretion (Harayama et al., 2014)
