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used mass spectrometry-based phosphoproteomics to create an atlas of the human kinome, revealing how tumors systematically hijack particular subnetworks through aberrant phosphorylation

Chrysanthemum morifolium polysaccharides protect intestinal microecology by boosting anti-inflammatory factors (IL-13, IL-10, IL-4) and lowering pro-inflammatory factors (IL-6, TNF-a, IL-17, IL-23, IL-1, IFN- )

In the following sections, the various direct mechanisms of acrolein toxicity such as protein and DNA adduction, and indirect mechanisms including induction of oxidative, mitochondrial, and ER stress, are critically discussed with possible connection to affected organs and pathological conditions

It was hypothesized that these structural changes might be associated with the impairment of the endogenous scavenging pathways