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Description
point out that AED and AEDG suppress caspase-dependent apoptosis, which increases as cell cultures age [66]
With age, mitochondria undergo a progressive deterioration, manifesting as changes in mitochondrial morphology, abundance, and OXPHOS activity 3,4
In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion
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