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doi: 10.3109/15563650.2013.802797
178,179 Additionally, cAMP can activate Rap1 through EPAC (Exchange Protein directly Activated by cAMP), 180,181,182 which is involved in regulating insulin secretion
Furthermore, IR increases hepatic De novo lipogenesis (DNL) and stimulates adipose tissue to secrete adipokine and inflammatory cytokine, ultimately leading to the dysregulation of adipose tissues lipolytic processes [26]
Nutraceuticals are combinations of essential nutrients and are becoming a part of novel medical treatments despite the lack of regulation
