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A static representation of the topology and electrostatic field in the H-site (Warshel, 1998) will have to be complemented with a description of the dynamics of the entire molecule ( Substrate Discrimination in Promiscuous Enzymes GSTs, like many other enzymes involved in detoxication, are promiscuous such that they can act on several different substrates and catalyze many alternative chemical reactions

Selenium glycinate supplementation increases blood glutathione peroxidase activities and decreases prostate-specific antigen readings in middle-aged US men

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This was followed by the addition of 300 l of water and the resulting suspension was centrifuged at 18,500 g for 10 minutes at 4 C