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Description
Figure 4 Molecular alterations in a target protein can also result in acquired drug resistance, such as crizotinib resistance in lung adenocarcinoma, which occurs due to a secondary mutation (G2032R) in the reactive oxygen species (ROS) proto-oncogene 1 (ROS1) kinase domain (75)

Copyright 2011

Pretreatment with FG-4592 was found to attenuate folic acid-induced renal ferroptosis via a mechanism involving NRF2 activation [101]

As verified by Gul et al
