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It is reported that treatment of CRC cells with luteolin, a naturally occurring flavonoid which is an agonist of PPAR, increased mRNA and protein expression of OCTN2 in a time- and dose-dependent manner, enhancing the intracellular accumulation of oxaliplatin (Qu et al., 2014)

These MAPKs phosphorylate a variety of substrates, leading to modulation of several cellular processes (89)

After overnight fasting, atrial tissues and blood samples were collected from euthanized mice for further analysis
