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Engelen, and Nicolaas E.P

Dysregulation of NF-B activity is associated with inflammation-related diseases and cancer ( The NF-B family includes five related transcription factors, and common NF-B protein is referred to homologous or heterodimers composed of p65/p50 subunit ( H 2 O 2 can deactivate IKK, which may be mediated through oxidation of IKK at cysteine 179 by ROS

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DPF2 is an essential component of the hematopoiesis-specific BAF (SWI/SNF) chromatin remodeling complex
