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However, excess ROS production can lead to oxidative stress (OS) (Grimm and Eckert, 2017), which causes damage to lipids, proteins and deoxyribonucleic acid (DNA), leading eventually to inflammation, apoptotic cell death, and tissue damage (Fig

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Mahonia aquifolium The extract of Mahonia aquifolium (Oregon grape) has been shown to inhibit keratinocyte proliferation and reduce the production of pro-inflammatory cytokines such as IL-8

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