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Hypothetically, both serine and glycine can equally donate one-carbon groups, however, the actual contribution of serine and glycine is far more complex

In brief, 2,3-DPG function is related to its capacity to stabilise deoxyhemoglobin T-state and lower intracellular pH

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[DOI] [PMC free article] [PubMed] [Google Scholar] 112.Ubellacker J.M., Tasdogan A., Ramesh V., Shen B., Mitchell E.C., Martin-Sandoval M.S., Gu Z., McCormick M.L., Durham A.B., Spitz D.R., Zhao Z., Mathews T.P., Morrison S.J
