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Likewise, NACs neuroinflammatory benefits could be studied in the older adult population, with a focus on postoperative delirium and cognitive dysfunction alongside analgesia particularly given the role of traditional opioid therapies in worsening these outcomes

Are there any interactions with other drugs

In addition, in experimental models, melatonin ameliorated the severity of multiple sclerosis (MS) [253] and improved survival time in amyotrophic lateral sclerosis (ALS) [254]

These findings collectively demonstrate that targeting signaling pathways such as JAK/STAT and PPAR represents a promising strategy for modulating macrophage polarization and related diseases
