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Description
Nature 606 , 791796 (2022)
Candidate Biomarkers for Neurological Symptoms Neurological symptoms are common in LC [20] and are associated with increased levels of proinflammatory cytokines IL-6, MCP-1 and TNF- in certain patients [300]
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Persistent AGERAGE activation can enhance cytokine production and ROS accumulation, creating a microenvironment that favors TGF-1 activation, extracellular matrix deposition, and fibrotic remodeling (145)
