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[9] In order for synaptic plasticity to be input-specific, these synaptic tags are essential on post-synaptic targets, to ensure synaptic potentiation is localized

doi: 10.5603/ARM.28099 45 FitzpatrickAMTeagueWGHolguinFYehMBrownLAS
Also, research shows that B12 absorbs best when dissolved in an isotonic solution like saline

Their direct contact with circulating copper and pro-oxidants (e.g., ox-LDL), combined with limited copper export capacity, creates a precarious copper balance [151, 152]
