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Leticia Prates Roma acknowledges funding from the DFG in the framework of the TRR219, project number 322900939

Thus, the enzyme catalyzes the hydroxylation of the substrate, forming a superoxide radical that decarboxylates 2-OG, forming a ferryl intermediate, which helps to bring iron to its active state (Fe 2+ )

It is based on a naturally

Melatonin prevents cytosolic calcium overload, mitochondrial damage and cell death due to toxically high doses of dexamethasone-induced oxidative stress in human neuroblastoma SH-SY5Y cells
