bpc-157 multiple sclerosis trial Multifunctionality and Possible Medical Application of the BPC 157 Peptide—Literature and Patent Review JPP No 5/2013 article 09

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Mechanisms of action Anti-CD38 antibodies exert their therapeutic effects via direct effector mechanisms on MM cells (i.e., CD38 enzymatic inhibition, direct induction of apoptosis) and through Fc-dependent immune mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), complement-directed cytotoxicity (CDC), and antibody-directed cellular phagocytosis (ADCP) (Fig