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Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes
Its protective efficacy can be attributed to its dual role: acting as a direct scavenger of reactive oxygen species (ROS) and serving as a precursor for glutathione (GSH) synthesis [32, 33]
FEBS J 276(15):39303941
It has been suggested that the capacity to reduce iron is not strongly correlated with the radical-quenching processes (H-atom transfer, HAT) that most antioxidants mediate
