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Probio-M8 improved microbial interactions (e.g., among Bifidobacterium , Eubacterium , Cyanobacterium , and Ruminococcus ) within the GM of PMOP, specifically enhancing butyrate synthesis while diminishing the prevalence of Ruminococcus , which has been inversely connected with OP (71)

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However, in our series, covering a time span of 3 weeks, no significant differences in the immunological outcome between overweight and nonoverweight participants were detectable, which underlines our in vitro findings pointing out direct immunomodulatory effects of BHB

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