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457 showed that pHLIP-Ku80 (), which was created by covalently conjugating pHLIPs with PNA targeting KU80 via disulfide bonds, could selectively reduce Ku80 expression under acidic conditions

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In a study by Huang et al., in 2022, miR-134-5p was found to be upregulated in bronchopulmonary dysplasia (BPD) in preterm infants, leading to ROS and Fe 2+ accumulation and GPX4 downregulation in these patients
