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Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations
Glutathione peroxidase 4 (GPX4), a key enzyme in lipid peroxide repair, reduces lipid peroxides by consuming GSH, thereby converting potentially toxic lipid hydroperoxides into non-toxic lipid alcohols ( In recent years, understanding of ferroptosis-related mechanisms has progressively deepened
It is an approved antineoplastic agent, and has been investigated as a cancer treatment 100
