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Clin Endocrinol (Oxf) (2011)

In: Gendelman HE, Ikezu T (eds) Neuroimmune pharmacology and therapeutics

Oxidative stress happens when your body is out of balance between free radicals and antioxidants

[ 38 ] In contrast, antioxidants, such as vitamins C and E and Nacetylcysteine (NAC), prevent BACH1 degradation and inhibit the release of free heme by lowering ROS levels, [ 39 ] since ROS stimulates free heme release through the oxidization of hemecontaining proteins
