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B., Kim, C

Homozygous null deletion of the Kat6a gene in mice causes foetal to perinatal death (depending on the genetic background), characterised by cleft palate, shortened jaws, cardiac septum defects, and interrupted aortic arch, as well as an anterior homeotic transformation of 19 body segments affecting the vertebral column and the nervous system (Voss et al, 2009, 2012

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Our group has determined the neuroprotective effects of ALCAR (100 mg/kg administered by subcutaneous injection) at 0, 4, 24 and 48 hours after HI on postnatal day 7