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Normalization of hematocrit levels using therapeutic phlebotomy is the most common approach for reducing the incidence of thrombotic complications, a therapy which exacerbates iron deficiency, contributing to a variety of non-hematological symptoms

Considerations: Exceeding daily doses of vitamin B12 beyond 10 mcg may induce a hematologic response in patients with folate deficiency

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Vitamin B12 appears in the milk of nursing mothers in concentrations that approximate the mother's vitamin B12 blood level

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