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ER stress is known to be implicated in the pathology of many inflammatory disease models, including LPS-induced lung inflammation (Kim et al., 2013), high-fat diet-induced insulin resistance (Yuzefovych et al., 2013), or chronic graft-versus-host disease (Mukai et al., 2017)

However, every treatment has some downsides

Iran J Plant Physiol 3:611617 Malekzadeh P, Khosravi-Nejad F, Hatamnia AA et al (2017) Impact of postharvest exogenous -aminobutyric acid treatment on cucumber fruit in response to chilling tolerance
