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Description
According to the Catalogue of Somatic Mutation in Cancer (COSMIC) database, NF1 is among the 20 most frequently mutated genes in GBC, with a somatic mutation frequency of 5%, based on the sequencing of nearly 300 samples (Fig
Non-tumor cell clusters were annotated using three methods to produce robust cell assignments: 1) comparison against known cell markers
The hepatic handling of bilirubin also involves efflux transporters such as MRP1 , MRP3 , and MRP4 , which facilitate the return of bilirubin or its conjugates to the blood as regulatory mechanism
& Strauss, M
