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Oxidative stress is a shift in the balance between oxidants and antioxidants in favour of oxidants [6]
The TKTL1 encoded protein lacks 38 amino acids, compared to the TKT protein, in the TPP-binding region
Furthermore, many lipidomic studies have demonstrated that PD-specific lipids are significantly altered in the brains and plasma of patients with PD, such as alterations in the lipid composition of lipid rafts in the frontal cortex
J Thorac Cardiovasc Surg 164(5):1327-1337, 2022
