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The peptide down-regulated oxidative phosphorylation, suppressed MYC target genes, and attenuated PI3K-AKT-mTOR signalingpathways classically inhibited in validated lifespan-extending interventions
On the neurological side, the pro-inflammatory factor released by AT may have first caused ferroptosis in the vagus nerve by inhibiting of the NRF2-GPX4 pathway, resulting in disorders of the autonomic nervous system
Acknowledgments We would like to thank the EEA Grants, project No
