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Ethacrynic acid and quinine, which are both GST inhibitors, have been reported to reverse the resistance to melphalan and doxorubicin of cancer cell lines with increased GST expression [25]

As of April 2026, BPC-157 is not explicitly listed on the World Anti-Doping Agency (WADA) Prohibited List by name, though WADA's catch-all S0 category (non-approved substances) captures any compound without regulatory approval for human therapeutic use

The most studied mechanism is the effects of Hg on oxidative stress and mitochondrial dysfunction

However, presumably to accommodate ()-catechin ( 12 ), the active site is substantially enlarged by a shift of the 4 and 4 helices by up to 1.71 (Fig