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Anal Chim Acta 247:125132 [Google Scholar] Kzlta H, Bingol Z, Goren AC, Pnar SM, Alwasel SH, Glin (2021a) LC-HRMS profiling of phytochemicals, antidiabetic, anticholinergic and antioxidant activities of evaporated ethanol extract of Astragalus brachycalyx FISCHER

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AMPK regulates carbohydrate metabolism by increasing GLUT 4-dependent glucose uptake through i ) phosphorylation of the Rab-GTPase-activating proteins AS160/TBC1D1 (60) and ii ) increasing the glycolysis-stimulator fructose-2,6-bisphosphate concentrations through phosphorylation of specific 6-phosphofructose-2-kinase isoforms (61)

Gut-flora-dependent metabolite trimethylamine-N-oxide promotes atherosclerosis-associated inflammation responses by indirect ROS stimulation and signaling involving AMPK and SIRT1