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Selective coactivation of 7- and 42-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction

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At week 16, patients who did not meet the American College of Rheumatology criteria for 20% improvement (ACR20) were switched from 15mg of oral MTX to 15mg of SC MTX and from 15mg of SC MTX to 20mg of SC MTX for the remaining 8 weeks, still in a blinded manner

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Nature 567 , 118122 (2019)

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Peroxynitrite causes endothelial cell monolayer barrier dysfunction [J]

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