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10.1097/DAD.0000000000001266 45 MayE.JodlS
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Our research group demonstrated that MOTS-c treatment significantly attenuated vascular calcification by activating the AMPK signaling pathway and suppressing the expression of the AT-1 as well as ET-B receptors [28]
Indeed, metformin is the most widely used oral insulin-sensitizing agent, being prescribed to more than 100 million people worldwide, including patients with prediabetes, insulin resistance, and polycystic ovary syndrome
