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As a key commensal bacterium for maintaining gut barrier integrity, the reduction of Akkermansia may exacerbate hyperandrogenemia and ovulatory dysfunction in PCOS by increasing LPS translocation, triggering ovarian macrophage pyroptosis and interferon- (IFN-)-mediated inflammatory responses, thereby disrupting steroid hormone synthesis, promoting granulosa cell apoptosis, and exacerbating hyperandrogenemia and ovulatory dysfunction in PCOS

Thus - urine testing measures both the presence of toxins as well as the ability to excrete

Many people report feeling a difference in their energy or seeing a shift in skin clarity within 4 to 8 weeks of consistent use