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doi: 10.1016/j.scr.2010.11.003
Vitamin B12 deficiency in DNA synthesis reduction is explained by the folate trapping theory as methyl-tetrahydrofolate.(...) methionine synthase cannot be activated and folate remains as methyl-FH4, which also causes a functional folate deficiency, thus explaining megaloblastic anemia." SOURCE: Interrelation of Vitamin B12 and Folic Acid
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