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The work identified the TNF- receptor as a promising AD target, and etanercept, a recombinant DNA-based anti-TNF- drug, reduces AD development, supporting anti-inflammatory strategies in AD ( Another promising AD therapeutic approach is employing monoclonal antibodies (mAbs) that target the amyloid plaques

Biochemical Evaluation The lung, kidney, and the liver samples were quickly frozen in liquid nitrogen and then kept at 80 C in a deep freezer until they were analyzed for total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), and paraoxonase-1 (PON-1)

A genetic polymorphism of the human dopamine transporter determines the impact of sleep deprivation on brain responses to rewards and punishments

doi:10.5056/jnm.2011.17.3.274 154