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The World Health Organization states that: No controlled studies have been published demonstrating systemic adverse effects from amalgam restorations [silver fillings]. In turn, the American Dental Association supports the use of dental amalgam as a safe, affordable, and durable material

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Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

and Weigel, D., "On reconciling the interactions between APETALA2, miR172 and AGAMOUS with the ABC model of flower development", Development 137 (21): 3633-3642 (2010)
