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It could be stress, a lack of (or too much) exercise, a buildup of environmental toxins, or an undiagnosed infection

The article on how long peptides last at room temperature quantifies this degradation rate, and the answer is sobering for anyone who has been careless with storage

In that case, sterile water for injection (SWI) is the alternative but you'd need to reconstitute fresh for each dose or within 24 hours

There is no established upper tolerable limit for B12 intake, though adverse reactions can occur in some individuals
