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This was a Phase 1B, double blind, randomized, placebo controlled, multiple-dose study with three cohorts

Subsequent phosphorylation of C-terminal tyrosines (Y1349 & Y1356) creates a multifunctional docking site that recruits signal transducing proteins including GAB1 and GRB2

Limitation: fiber enrichment complicates attribution

doi: 10.1155/2019/4951379 7 ChaY.ParkT.-Y.LeblancP.KimK.-S