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Thus, unneutralized ROS produced in the brain mitochondria of autistic individuals form a positive feedback, a vicious cycle, leading to incrementally growing damage to the mitochondria, which may ultimately result in cell death

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For example, during nutrient deprivation or increased energy demand, signaling pathways such as the AMP-activated protein kinase (AMPK) pathway may induce phosphorylation, enhancing the enzyme's activity to promote fatty acid oxidation

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