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Highlights The scientists used a compound called 5-amino-1MQ to inhibit an enzyme called NNMT that plays a role in breaking down a precursor to NMN in the NAD+ synthesis pathway

Doses of pyridoxine as low as 5-10 mg can antagonize levodopas effect if carbidopa is not present, so caution is warranted and any supplemental B beyond the nutritional dose should be under medical guidance

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Many individuals seek treatment after experiencing persistent neuropathy symptoms and finding limited relief from general pain medications
