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As a rationale, the study proposed the evidence that stimulation of the Caco-2 cells with 10100 M BPC 157 resulted in an earlier, reproducible stimulation of the expression of mRNA for egr-1, with a peak after 15 min
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In an open uncontrolled trial in 20 men with idiopathic infertility and a low testosterone-to-estrogen ratio, three months of treatment with letrozole resulted in improved sperm motility and morphology, reduced sperm DNA fragmentation, increased testosterone-to-estrogen ratio, and four spontaneous pregnancies
