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Its applicability in the rapid upgrading of the collateral pathways may likely provide an additional beneficial effect for the heart functions, and various vessel tributaries, and normalization/attenuation of the intracranial (sinus sagittal) hypertension, portal and caval hypertension and aortal hypotension, and counteraction of the multiorgan failure syndrome [18,19,23,24,27,28,29,31,37,38,39,40]

This review discusses the development of novel antiobesity drugs based on current understanding of energy homeostasis Keywords: Obesity, Pharmacotherapy, Drug targets

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