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As the core of energy metabolism, the TCA cycle exhibits abnormalities primarily stemming from insufficient substrate supply and inhibited activity of key enzymesultimately leading to reduced energy production efficiency and dysregulation of metabolic intermediates (89)

Based on this assumption, 1.36 g L 1 (9.24 mM) glutamate may be maximally produced in the KDC (containing 41.6 mM glucose) medium by the CgCS+CitS strain, which was used to evaluate glucose-based productivity

Gemcitabine resistance was also associated with GPX4 in PDAC cells

Due to the current regulatory framework in the supplement industry, USADA is not able to tell athletes what dietary supplement products are safe to take