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The product shall not be used as an advanced pharmaceutical intermediate (API) or investigational drug or a biologic

Glycogen synthase kinase-3 is also an endogenous inhibitor of guanine nucleotide exchange factor eIF2B, an essential participant in the initiation of protein translation

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Front Neurol 5:237 Ding K et al (2014) Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2-ARE signaling pathway as a potential mechanism
