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It's like having a repair technician for your main defender

1 Introduction Cellular redox homeostasis depends on a dynamic equilibrium between prooxidant production and its elimination
GRP78, also known as immunoglobulin heavy chain binding protein (BIP), is one of the main chaperone proteins in the endoplasmic reticulum (ER) ( , ( , (Figure 5)

The decrease in antioxidant system capacity weakens the antioxidant defense of ARDS patients and makes them more susceptible to oxidative stress damage