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Description
Step-by-step Hypothalamus releases GHRH GHRH binds to GHRH receptors on pituitary somatotrophs This activates Gs protein signalling Gs activates adenylate cyclase cAMP increases cAMP activates protein kinase A GH is released from pituitary cells Simplified: GHRH GHRH receptor cAMP signalling Growth hormone release Peptides like: CJC-1295 Tesamorelin mimic GHRH receptor activation

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