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doi: 10.1172/JCI21134 289 SitaramanSLiuXCharrierLGuLHZieglerTRGewirtzAet al

In this review, we summarize (i) the pathophysiological mechanisms of vascular aging and arterial stiffness, (ii) outline the resulting end-organ damage, (iii) present different methods for the measurement of arterial stiffness, (iv) highlight the potential role of prevention and therapy, and (v) provide future perspectives for arterial stiffness research

Symptoms vary widely depending on the location and severity of the herniation

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