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Shoulder pain affects up to a third of people at some point in their lives [1]

Reduced sarco/endoplasmic reticulum Ca 2+ ATPase activity plays a role in cardiac senescence onset

However, contrary to expectations, the deletion of the Nfe2l2 gene had a moderate impact on the course of the disease in SOD1 G93A mice and negatively affected only a few Nrf2-regulated antioxidant enzymes, thus suggesting that several Nrf2-target genes can also be regulated independently of Nrf2 in ALS mice [270, 271]

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Schulte M.H.J., Wiers R.W., Boendermaker W.J., Goudriaan A.E., van den Brink W., van Deursen D.S., Friese M., Brede E., Waters A.J