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According to the glutamate hypothesis, dysfunction of NMDA receptormediated neurotransmission has been implicated in the pathophysiology of negative symptoms in schizophrenia (Hu et al
doi: 10.1016/j.jaad.2017.09.053
doi: 10.1517/14740338.2.4.347 207 HPG
Vitamins A and D also improve gut barrier integrity through modulating TJ protein expression, with reduced vitamin A consumption in rats resulting in impaired TJ barriers most likely a consequence of the decreased expression of ZO-1 and occludin also reported
