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A big challenge is the metabolic adaptation of cancer cells that can survive also under stress conditions, such as Glutamine withdrawal (87, 88)

A study reported that individuals with AD exhibit reduced microbial diversity and an increased abundance of Proteobacteria (49), and elevated levels of Fusobacteriota have been suggested as potential biomarkers for AD (50)

The difference is architectural, mechanistic, and clinically meaningful

Brookens SK, Boothby MR