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These critical modifications confer a slightly higher affinity to the GLP-1 receptor for both peptides, enabling lower concentrations to achieve equivalent receptor occupancy compared to native GLP-1 [13]

Plasma selenium over time and cognitive decline in the elderly

In addition, p53 is known to negatively regulate cellular glycolysis by directly or indirectly inhibiting the expression of glucose transporters (GLUTs) or the translocation of GLUT1 to the plasma membrane, leading to decreased glucose uptake [62,63,64]

Polyhexamethylene guanidine aerosol triggers pulmonary fibrosis concomitant with elevated surface tension via inhibiting pulmonary surfactant