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Description
Meanwhile, the expression of Nrf2 is suppressed by Glutathione S-transferase zeta 1 (GSTZ1), which ia an enzyme in the catabolism of phenylalanine significantly downregulated in sorafenib-resistant hepatoma cells (Wang Q

A loading phase of 4 to 6 weeks at the higher end of the range is common, followed by a maintenance dose of 1 mg/day three to five times per week

Target Concerns: - Heart health
This makes it particularly valuable for patients whose skin sensitivity limits their use of more aggressive actives like retinoids